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We found that AA-exposed mice exhibited significantly greater airway hyperreactivity compared to PBS and melatonin-only controls ( Figure 1O ), alongside reduced dynamic compliance ( Figure 1P )

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Consequently, research has shown evidence that helminth GSTs may have key roles in the establishment of infection and the development of anthelmintic resistance, as demonstrated in the parasitic flatworm Fasciola hepatica (Chemale et al ., Reference Chemale, Perally, LaCourse, Prescott, Jones, Ward, Meaney, Hoey, Brennan, Fairweather and Trudgett2010